Mucocutaneous leishmaniasis is a rare disease in Europe. Relapses afte
r treatment are more frequent than in visceral leishmaniasis. HIV pati
ents infected by Leishmania have frequently visceral involvement, and
responses to treatment are poor. Mucocutaneous leishmaniasis in HIV-in
fected patients has rarely been reported. A patient with centrofacial
granuloma was diagnosed as having mucocutaneous leishmaniasis; simulta
neously HIV infection was detected. To our knowledge this is the first
case acquired in Europe. Intravenous meglumine antimonate 20 mg/kg/da
y for 28 days was proven to be useful.