M. Cachovan et al., EFFICACY OF A STANDARDIZED PHYSICAL-TRAIN ING PROGRAM IN INTERMITTENTCLAUDICATION, Wiener Klinische Wochenschrift, 106(16), 1994, pp. 517-520
In stage II peripheral arterial occlusive disease (PAOD) physical trai
ning is generally the therapy of choice if no reopening procedures are
indicated. The aim of this pilot study was to ascertain the increase
in claudication distance due to the exclusive implementation of an int
ensive exercise programme under standardized conditions, for a planned
double blind placebo controlled study regarding the efficacy of pharm
acotherapy in addition to physical training. 23 in-patients (median ag
e 62 years) with an absolute claudication distance on treadmill of bet
ween 50 m and 200 m (12% inclincation, 3 km/h walking speed) participa
ted 5 days a week in the following intensive standardized physical tra
ining programme: in the morning and afternoon supervised gymnastics fo
r about 30 minutes, followed by 2 cycles of treadmill exercise each am
ounting to 66% of the absolute claudication distance. After a training
programme of 4 weeks the mean initial claudiaction distance rose sign
ificantly from 83 m to 134 m (61%), as did the mean absolute claudicat
ion distance from 127 m to 222 m (75%). If an increase in claudiaction
distance of at least 60% is taken as criterion of efficacy, 48% of th
e patients can be defined as responders. After completion of personal
inquiries 62% of the patients were willing to participate in a similar
training programme again.