COMPLIANCE WEIGHT DEFICIT INDEX - COMBINING UMBILICAL ARTERY RESISTANCE AND GROWTH DEFICIT FOR PREDICTING INTRAUTERINE GROWTH-RETARDATION AND POOR PERINATAL OUTCOME
Ad. Kofinas et al., COMPLIANCE WEIGHT DEFICIT INDEX - COMBINING UMBILICAL ARTERY RESISTANCE AND GROWTH DEFICIT FOR PREDICTING INTRAUTERINE GROWTH-RETARDATION AND POOR PERINATAL OUTCOME, Journal of reproductive medicine, 39(8), 1994, pp. 595-600
One hundred sixty-sia patients underwent examination of the umbilical
artery (LIA) by continuous wave Doppler ultrasound one week prior to d
elivery. The UA compliance deficit (CD) and weight deficit (WD) were c
ombined into an index (CWDI) by a formula based on the Pythagorean The
orem, CWDI represents the hypotenuse, and CD and WD represent the two
perpendicular, lines of a triangle: (CWDI = root CD2 + WD2). Perinatal
outcomes were evaluated by the number of perinatal deaths, delivery f
or fetal indications prior to 37 weeks' gestation, Jive-minute Apgar s
core <7, neonatal intensive care unit (NICU) admission and the presenc
e of intrauterine growth retardation (IUGR). A CWDI value of greater t
han or equal to 20 was the most discriminatory in identifying fetuses
with poor outcomes. Fetuses with CWDI greater than or equal to 20 were
more likely to be premature (P<.001) or growth retarded (P<.001) or h
ave lower Apgar scores (P<.005) and longer NICU stays (P<.001). Seven
of the eight perinatal deaths occurred in patients with abnormal CWDI
(P<.001). The sensitivity of an abnormal CWDI tons 95% for IUGR, 60% f
or preterm delivery, 82% for NICU admission, 90% for Apgar score <7 at
five minutes, 87% for perinatal mortality and 68% for overall poor pe
rinatal outcomes. CWDI is a sensitive index for the identification of
fetuses with IUGR and poor perinatal outcome.