MOHS MICROGRAPHIC EXCISION OF SEBACEOUS CARCINOMA OF THE EYELIDS

BACKGROUND. Sebaceous carcinoma of the eyelid is a difficult tumor to manage because of diagnostic difficulties and pagetoid-type spread in the conjunctivae. OBJECTIVE. We report our experience with eight patie nts using the Mohs technique of excision with reconstruction. METHODS. Six cases were managed with paraffin-embedded hematoxylin and eosin s ections. One case was managed by frozen histologic sections and one wa s managed with frozen section processing followed by paraffin-embedded section review.RESULTS. The correct pathologic diagnosis was made ini tially in only 50% of the cases. Eighty-eight percent of the cases rev ealed intraepithelial neoplasm. There has been one recurrence with met astatic disease. The average follow-up period has been 56.8 months. CO NCLUSIONS. We advocate early recognition and excision with the Mohs te chnique with paraffin-embedded sections followed by reconstruction. Th e use of paraffin-embedded histologic sections helps with interpretati on of intraepithelial and pagetoid tumor spread.