RELIABILITY OF THE SIMPLE 20-MINUTE WHOLE-BLOOD CLOTTING TEST (WBCT20) AS AN INDICATOR OF LOW PLASMA-FIBRINOGEN CONCENTRATION IN PATIENTS ENVENOMED BY BOTHROPS SNAKES

Authors
SANOMARTINS IS FAN HW CASTRO SCB TOMY SC FRANCA FOS JORGE MT KAMIGUTI AS WARRELL DA THEAKSTON RDG CARDOSO JLC LEITE RP NISHIOKA SA AVILA A SANTORO ML CHUDZINSKI AM KELEN EMA HIRATA MH MIRANDOLA RMS
Citation
Is. Sanomartins et al., RELIABILITY OF THE SIMPLE 20-MINUTE WHOLE-BLOOD CLOTTING TEST (WBCT20) AS AN INDICATOR OF LOW PLASMA-FIBRINOGEN CONCENTRATION IN PATIENTS ENVENOMED BY BOTHROPS SNAKES, Toxicon, 32(9), 1994, pp. 1045-1050
Citations number
13
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
32
Issue
9
Year of publication
1994
Pages
1045 - 1050
Database
ISI
SICI code
0041-0101(1994)32:9<1045:ROTS2W>2.0.ZU;2-5
Abstract
A simple whole blood clotting test (WBCT20) was assessed for its effic acy in determination of severe defibrinogenation in patients envenomed by Bothrops snakes in Brazil. There was a close relationship between the results of the WBCT20 and plasma fibrinogen levels in 69 moderatel y envenomed patients. The advantage of the WBCT20 over estimation of p lasma fibrinogen concentrations in patients is that it is a simpler, f aster and more reliable test. It is also of use in assessing the effec tiveness of antivenom therapy in relation to the restoration of blood coagulability.