THE USE OF LIPOSOMES IN THE INVESTIGATION OF MECHANISMS OF ASBESTOS DAMAGE

Authors
ERDOGDU G HASIRCI VN
Citation
G. Erdogdu et Vn. Hasirci, THE USE OF LIPOSOMES IN THE INVESTIGATION OF MECHANISMS OF ASBESTOS DAMAGE, Experientia, 50(8), 1994, pp. 785-787
Citations number
19
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Experientia → ACNP
ISSN journal
00144754
Volume
50
Issue
8
Year of publication
1994
Pages
785 - 787
Database
ISI
SICI code
0014-4754(1994)50:8<785:TUOLIT>2.0.ZU;2-2
Abstract
Asbestos-induced cell damage is initiated by a reaction at the plasma membrane. The effect of chrysotile (which is more hemolytic and releas es more silicic acid than other types of asbestos) on permeability cha nges of liposomes has been investigated. The destabilizing effect rise s when the amount of chrysotile is increased. Silicon dioxide is one m ajor constituent which could be a hemolytic agent, and a cause of dama ge. It also caused an increase of permeability of liposomes.