BRUXISM SECONDARY TO ANTIPSYCHOTIC DRUG EXPOSURE - A POSITIVE RESPONSE TO PROPRANOLOL

Citation
I. Amir et al., BRUXISM SECONDARY TO ANTIPSYCHOTIC DRUG EXPOSURE - A POSITIVE RESPONSE TO PROPRANOLOL, Clinical neuropharmacology, 20(1), 1997, pp. 86-89
Citations number
13
Categorie Soggetti
Clinical Neurology","Pharmacology & Pharmacy
Journal title
ISSN journal
03625664
Volume
20
Issue
1
Year of publication
1997
Pages
86 - 89
Database
ISI
SICI code
0362-5664(1997)20:1<86:BSTADE>2.0.ZU;2-5
Abstract
We present two cases of acute nocturnal bruxism occurring as an early side effect of antipsychotic drug treatment. The development of bruxis m was coupled with the appearance of neuroleptic-induced akathisia. Bo th complications were relieved after the P-adrenergic blocker proprano lol was added, suggesting the involvement of the adrenergic and seroto nergic central nervous systems, besides the dopaminergic system, in th e pathogenesis of bruxism. The positive response of iatrogenic bruxism to propranolol implies that propranolol also deserves a trial for the treatment of noniatrogenic nocturnal bruxism.