I. Amir et al., BRUXISM SECONDARY TO ANTIPSYCHOTIC DRUG EXPOSURE - A POSITIVE RESPONSE TO PROPRANOLOL, Clinical neuropharmacology, 20(1), 1997, pp. 86-89
We present two cases of acute nocturnal bruxism occurring as an early
side effect of antipsychotic drug treatment. The development of bruxis
m was coupled with the appearance of neuroleptic-induced akathisia. Bo
th complications were relieved after the P-adrenergic blocker proprano
lol was added, suggesting the involvement of the adrenergic and seroto
nergic central nervous systems, besides the dopaminergic system, in th
e pathogenesis of bruxism. The positive response of iatrogenic bruxism
to propranolol implies that propranolol also deserves a trial for the
treatment of noniatrogenic nocturnal bruxism.