ERADICATION OF CASEOUS-LYMPHADENITIS IN SHEEP WITH THE HELP OF A NEWLY DEVELOPED ELISA TECHNIQUE

The purpose of the study was to attempt to eradicate caseous lymphaden itis in sheep with the help of serological monitoring. A newly develop ed double-antibody sandwich ELISA and the culling of positive or doubt ful reactors was the basis of the disease control regimen. Seropositiv e pregnant ewes were kept in quarantine and removed after lambing; the ir lambs were artificially fed aod allowed to remain in the herd. Unde r this regimen, supplemented by a number of hygienic measures, caseous lymphadenitis was eradicated from two large flocks of sheep in which the disease was endemic.