Tb. Dodson et al., CRANIAL BONE-GRAFT TO RECONSTRUCT THE MANDIBULAR CONDYLE IN MACACA-MULATTA, Journal of oral and maxillofacial surgery, 55(3), 1997, pp. 260-267
Purpose: The purpose of this study was to evaluate the efficacy of cra
nial bone grafts to reconstruct the mandibular condyle in a nonhuman p
rimate model. Materials and Methods: The right mandibular condyle was
resected in eight female, adult, nongrowing monkeys (Macaca mulatta) a
nd the mandible was reconstructed with autogenous, full-thickness cran
ial bone harvested from the frontal area of the skull and stabilized w
ith rigid fixation, Joint function, facial symmetry, and occlusion wer
e evaluated preoperatively and over the course of 1 year postoperative
ly, The height of the bone graft was measured intraoperatively and al
1 year postoperatively. Results, Seven monkeys survived for 1 year, Th
e animals' weights were stable postoperatively, There were no statisti
cally significant changes in maximal incisal opening or lateral excurs
ion, as well as no statistically significant changes in facial symmetr
y or occlusion, On average, the total decrease in height of the graft
was 0.7 +/- 0.9 mm (P =.07). Conclusion: After reconstruction of the m
andibular condyle in Macaca mulatta, full-thickness cranial bone graft
s provided a functional joint that resisted resorption, Cranial bone m
ay therefore provide a suitable alternative to other autologous or all
oplastic graft materials for reconstruction of the human mandibular co
ndyle in nongrowing patients.