DELAYED VASOVASOSTOMY - EXPERIMENTAL-STUDY USING FIBRIN GLUE

Citation
O. Vankemmel et al., DELAYED VASOVASOSTOMY - EXPERIMENTAL-STUDY USING FIBRIN GLUE, European urology, 31(2), 1997, pp. 182-186
Citations number
19
Categorie Soggetti
Urology & Nephrology
Journal title
ISSN journal
03022838
Volume
31
Issue
2
Year of publication
1997
Pages
182 - 186
Database
ISI
SICI code
0302-2838(1997)31:2<182:DV-EUF>2.0.ZU;2-X
Abstract
We compared delayed vasectomy reversals performed in rats using fibrin glue combined with 3 transmural sutures or a conventional microsurgic al technique. Forty Sprague-Dawley rats underwent bilateral vasectomy followed 2 weeks later by bilateral vasovasostomy using fibrin glue or a conventional microsurgical suture technique. Our protocol evaluated fertility rates after a 3-week mating period, sperm granuloma formati on, histological changes at the anastomotic site, longitudinal tensile strength and mean testicular weight. The fibrin glue technique requir ed significantly reduced operative lime (p < 0.0005) and showed statis tically lower tensile strength performance (p < 0.0005). All other par ameters showed no statistical difference between the two techniques. F ibrin-glued vasovasostomy is efficient in a delayed protocol and deser ves further clinical experience.