PATHOLOGY OF THE VULVA AND VAGINA

Extensive clinical, epidemiologic and pathologic research published in the past year has enhanced our understanding of the pathogenesis and natural history of human papillomavirus induced female genital tract l esions, and refined diagnostic and therapeutic modalities in managemen t of these patients. Current experience with vulvar intraepithelial ne oplasia as well as diagnosis and treatment of squamous cell carinoma o f the vagina and vulva are discussed. Advanced imaging techniques and immunohistochemical studies are employed in diagnosis and classificati on of less common neoplasms. New antibioitics and potent topical stero ids are available for treatment of inflammatory vulvovaginitis, partic ularly in cases of recurrent candidiasis and lichen sclerosus. Persist ent or resistant vulvovaginitis may benefit from an interdisciplinary approach to diagnosis and treatment.