Gd2O2S phosphor screens between 250 and 1000 mg/cm(2) thick were evalu
ated for use in megavoltage imaging systems. The phosphor layers were
placed on brass plates ranging from 1 to 5 mm thick, each with and wit
hout an optical back reflector (white paint). Light output and spatial
resolution were measured at 6- and 23-MV x-ray energies. Light output
was found to increase linearly with phosphor thickness up to 500 mg/c
m(2), reaching a plateau at 1000 mg/cm(2). Spatial resolution [modulat
ion transfer function (MTF)] decreased exponentially with phosphor thi
ckness up to 750 mg/cm(2), where a minimum was reached. The variation
of MTF with phosphor thickness was found to obey a simple empirical re
lation.