EFFECT OF TREATMENT WITH CONTRACEPTIVE STEROIDS ON THE SEXUAL-BEHAVIOR OF RATS PRETREATED WITH BENZPYRENE OR ALLYLESTRENOL IN FETAL OR NEONATAL AGE

Treatments with contraceptive steroids significantly reduced the recep tivity of adult female rats. This effect was not observed in ovariecto mized females treated with high doses of estrogen and gestagen hormone s prior to the investigation. The receptivity was also significantly r educed in rats treated with steroids (allylestrenol or benzpyrene) in their fetal or neonatal age, as it was demonstrated in previous experi ments. The contraceptive treatment of the above described, pretreated adults resulted in improved function of receptivity, but it had no dif ference compared to the group which was only treated with anticoncipie nt. This means that neonatal treatment with allylestrenol or benzpyren e does not influence the effects of contraceptive steroids on the sexu al behaviour (receptivity). The two effects are not additive.