DERIVATIVE ULTRAVIOLET SPECTROPHOTOMERIC DETERMINATION OF PROCAINE HYDROCHLORIDE AND PYRIDOXINE HYDROCHLORIDE FROM SUGAR-COATED TABLETS

Authors
Citation
M. Surmeian, DERIVATIVE ULTRAVIOLET SPECTROPHOTOMERIC DETERMINATION OF PROCAINE HYDROCHLORIDE AND PYRIDOXINE HYDROCHLORIDE FROM SUGAR-COATED TABLETS, Revue Roumaine de Chimie, 39(5), 1994, pp. 497-501
Citations number
10
Categorie Soggetti
Chemistry
Journal title
ISSN journal
00353930
Volume
39
Issue
5
Year of publication
1994
Pages
497 - 501
Database
ISI
SICI code
0035-3930(1994)39:5<497:DUSDOP>2.0.ZU;2-B
Abstract
A method is described for the determination of procaine hydrochloride and pyridoxine hydrochloride from sugar-coated tablets by first and se cond-derivative UV spectrophotometry using as solvents water and 0.1 M hydrochloric acid respectively. The procedure was defined by regressi on analysis for a high number of standard solutions. Linear relationsh ips were obtained between the mixture composition and the amplitudes: dA/dlambda at 308.33 nm for procaine hydrochloride and d(s)A/dlambda2 at 265.81 nm for pyridoxine hydrochloride amount. The method, yielding accurate and precise results, was satisfactorily applied to laborator y mixtures and pharmaceutical preparation, ASLAVITAL(R) sugar-coated t ablets.