Exercise echocardiography, a versatile, noninvasive diagnostic test of
left ventricular wall motion performed at rest and under induced stre
ss, enables the cardiologist to detect and assess coronary artery dise
ase. Stress-induced ischemia is thereby expressed as left ventricular
regional wall motion abnormality. By using various physical (bicycle o
r treadmill exercise) and pharmacological (dipyridamole, dobutamine, a
denosine) stress inducers, the test provides information about the loc
alization and extent of coronary artery disease in addition to detecti
ng stress-induced coronary insufficiency. As regards diagnostic accura
cy in detecting coronary artery disease, stress echocardiography is su
perior to exercise electrocardiography and, according to the available
data, it is comparable to perfusion scintigraphic testing. Studies ha
ve demonstrated the clinical value of stress echocardiography in detec
ting residual stenosis after angioplasty, for diagnosing bypass dysfun
ction after heart surgery, for preoperative risk assessment in noncard
iac surgeries, and for obtaining prognostic information, e.g., after m
yocardial infarction. Preliminary studies have shown that pharmacologi
cal exercise echocardiography is able to identify viable myocardium in
the early phases after acute myocardial infarction. Furthermore, it i
s able to predict the functional success of revascularization in chron
ic regional left ventricular dysfunction. In addition to the wide rang
e of diagnostic possibilities in coronary artery disease, other notabl
e applications include stress testing for assessment of global left ve
ntricular pump function in patients with aortic regurgitation or cardi
omyopathy.