INULIN MEASUREMENT IN SERUM AND URINE WITH AN AUTOANALYZER, CORRECTEDFOR GLUCOSE INTERFERENCE

Citation
Egwm. Lentjes et al., INULIN MEASUREMENT IN SERUM AND URINE WITH AN AUTOANALYZER, CORRECTEDFOR GLUCOSE INTERFERENCE, European journal of clinical chemistry and clinical biochemistry, 32(8), 1994, pp. 625-628
Citations number
12
Categorie Soggetti
Biology,"Chemistry Medicinal
ISSN journal
09394974
Volume
32
Issue
8
Year of publication
1994
Pages
625 - 628
Database
ISI
SICI code
0939-4974(1994)32:8<625:IMISAU>2.0.ZU;2-Z
Abstract
A method is described for the semi-automated measurement of inulin con centrations in serum and urine in the presence of glucose. The concent ration of glucose is measured simultaneously and is used to correct fo r almost all ''inulin-like'' interferences, The inulin standard curve is linear over a wide range (5-2500 mg/l). Between-run precision is < 6% and recovery from spiked sera is 98%. This method offers the possib ility of measuring glomerular filtration rate in patients with varying glucose concentrations (e. g. diabetics).