EARLY-ONSET AND LATE-ONSET PELVIC-INFLAMMATORY-DISEASE AMONG WOMEN WITH CERVICAL CHLAMYDIA-TRACHOMATIS INFECTION AT THE TIME OF INDUCED-ABORTION - A FOLLOW-UP-STUDY
Jl. Sorensen et al., EARLY-ONSET AND LATE-ONSET PELVIC-INFLAMMATORY-DISEASE AMONG WOMEN WITH CERVICAL CHLAMYDIA-TRACHOMATIS INFECTION AT THE TIME OF INDUCED-ABORTION - A FOLLOW-UP-STUDY, Infection, 22(4), 1994, pp. 242-246
After termination of a double-blind, randomized study on erythromycin
in the prevention of post-abortion infection, 34 women (14 treated wit
h erythromycin, 20 not treated with erythromycin) harbouring Chlamydia
trachomatis were followed up within 6 weeks and again 2 to 24 months
after the abortion in order to detect an early- and late-onset pelvic
inflammatory disease (PID). For statistical analysis survival analysis
by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untrea
ted women with C. trachomatis infection at the time of abortion had a
cumulative risk of 72% of developing early and/or late PID, if observe
d for 24 months. This cumulative risk was significantly reduced to 8%
if the C. trachomatis infection was treated at the time of the abortio
n. Screening for and treatment of C. trachomatis is warranted, expecia
lly in women less than or equal to 25 years old, to avoid early and la
te-onset PID after induced first trimester abortion.