ENANTIOMER SEPARATION OF SIDE-CHAIN FLUORINATED ALKYLBENZENES BY CAPILLARY GAS-CHROMATOGRAPHY ON CYCLODEXTRIN PHASES

The separation of racemic side-chain fluorinated alkylbenzenes and bro mofluorinated analogues by capillary gas chromatography using permethy lated alpha, beta and gamma-cyclodextrins dissolved in polysiloxanes o f different polarity as stationary phases is described. The influence of the achiral polysiloxane matrices on the separation of enantiomers is discussed in the light of the results obtained with the different p hases. For a part of the tested compounds thermodynamic data are deter mined which describe the interaction of enantiomers with the stationar y phase. The mechanism of separation is discussed on this basis and by comparison with data for structurally similar compounds.