MODEL FOR AN IMMOBILIZED OXIDASE ENZYME ELECTRODE IN THE PRESENCE OF 2 OXIDANTS

In mediated oxidase electrodes, the artificial electron acceptor compe tes with oxygen for the reoxidation of the enzyme. A steady-state mode l for a three-substrate electrode is employed to investigate the influ ence of oxygen on the current response of an amperometric enzyme elect rode and concentration profiles predicted in the enzyme layer for the substrates. The model predicts the electrode response for different O- 2 levels, and the influence of model parameters on the electrode perfo rmance is tested and discussed with the view of improved sensor design .