COMPUTER ANALYSES SUGGEST INTERACTIONS OF NONMUSCLE FILAMIN WITH LIPID-MEMBRANES

Authors
TEMPEL M GOLDMANN WH ISENBERG G
Citation
M. Tempel et al., COMPUTER ANALYSES SUGGEST INTERACTIONS OF NONMUSCLE FILAMIN WITH LIPID-MEMBRANES, FEBS letters, 350(2-3), 1994, pp. 169-172
Citations number
13
Categorie Soggetti
Biophysics,Biology
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
350
Issue
2-3
Year of publication
1994
Pages
169 - 172
Database
ISI
SICI code
0014-5793(1994)350:2-3<169:CASION>2.0.ZU;2-4
Abstract
It is concluded from structure predictions of the primary amino acid s equence by computer analyses that two segments of non-muscle filamin c ould facilitate lipid membrane attachment or anchoring. Residues 49-71 of the amino-terminal may attach to phospholipid membranes, and resid ues 131-155 may anchor in the hydrophobic region of lipid membranes.