SYNTHESIS AND CATALYTIC PROPERTIES OF AN ACYCLIC ANALOG OF HYDROXY NORPHOS

Authors
BORNER A WARD J RUTH W HOLZ J KLESS A HELLER D KAGAN HB
Citation
A. Borner et al., SYNTHESIS AND CATALYTIC PROPERTIES OF AN ACYCLIC ANALOG OF HYDROXY NORPHOS, Tetrahedron, 50(35), 1994, pp. 10419-10430
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
35
Year of publication
1994
Pages
10419 - 10430
Database
ISI
SICI code
0040-4020(1994)50:35<10419:SACPOA>2.0.ZU;2-S
Abstract
The synthesis of (S)-1,2-bis(diphenylphosphino)butane-4-ol 1 an acycli c analogue of hydroxy norphos is described, starting from L-ascorbic a cid. Problems which arose during the cleavage of OH-protective groups in the presence of phosphino groups are discussed. The hydrogenation p roperties of the catalyst derived from the new ligand are compared wit h those obtained with hydroxy norphos.(1)