EFFECT OF 4-KHZ TONE EXPOSURE ON THE GUINEA-PIG INNER-EAR - RELATION IN THE CHANGE OF COCHLEAR MICROPHONICS, ACTION-POTENTIAL, ELECTROCHEMICAL POTENTIAL AND K+ ION CONCENTRATION INDUCED BY NOISE EXPOSURE
T. Sugisawa et al., EFFECT OF 4-KHZ TONE EXPOSURE ON THE GUINEA-PIG INNER-EAR - RELATION IN THE CHANGE OF COCHLEAR MICROPHONICS, ACTION-POTENTIAL, ELECTROCHEMICAL POTENTIAL AND K+ ION CONCENTRATION INDUCED BY NOISE EXPOSURE, ORL, 56(5), 1994, pp. 263-268
Using 110 male albino guinea pigs, and applying electrophysiological m
ethods, we investigated the effects of 4 kHz tone at moderate sound pr
essure level on the inner ear at different exposure times (6, 12, 24 a
nd 48 h). Longer than 12 h exposure to 4 kHz tone had a considerable e
ffect on the hearing, inducing a decrease in the maximum output voltag
e of cochlear microphonics and an increase in the K+ concentration in
the endolymph.