The present research was aimed at defining the surgical anatomy of the
biliopancreatic ducts and of Oddi's sphincter. The numerous anatomic
variations of the papilla, the millimetric distribution of its muscle
fibres, and any morphological detail of clinical significance have bee
n investigated. An integrated analysis of radiographic, tridimensional
(casts), and histologic findings has been carried out in 49 of 64 aut
optic bilio-duodeno-pancreatic specimens. Exact limits of the choledoc
us and Wirsung sphincters were defined. A consistent accumulation of c
ircular muscle fibres could be seen, on the choledocus duct side, up t
o a mean distance of 13.6 mm from the papillary pore. However, more ra
refied fibres were present up to 20.5 mm. Muscle fibres were seen to s
top roughly on the pancreatic duct side at 7.3 mm from the papillary p
ore. The beginning of the sphincter was observed 2-3 mm above the papi
llary pore. There was no evidence suggesting the presence of upper, mi
ddle, and lower biliary sphincters. Five anatomic diversities of the W
irsung-choledocus confluence were found. The Y type was the most frequ
ent (61.2%), followed by the U type (22.4%), V (14.3%), and II (2.1%).
Santorini's duct with a normal papilla was present in 16 per cent of
the cases. These data along with other interesting observations on ant
ireflux mechanisms (Santorini's valves) and on the ductal space orient
ation appear to be useful guidelines for a physiopathological understa
nding of bilio-pancreatic diseases and for any therapeutic procedure o
n these structures.