A CONCISE SYNTHESIS OF 2 PYRROLES OF MARINE ORIGIN

Authors
JEFFORD CW SIENKIEWICZ K THORNTON SR
Citation
Cw. Jefford et al., A CONCISE SYNTHESIS OF 2 PYRROLES OF MARINE ORIGIN, Tetrahedron letters, 35(34), 1994, pp. 6271-6274
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
34
Year of publication
1994
Pages
6271 - 6274
Database
ISI
SICI code
0040-4039(1994)35:34<6271:ACSO2P>2.0.ZU;2-J
Abstract
2-Ethanolamine and (2R)-2-aminopropanol were converted into their N-py rrole derivatives, 14 and 15, by reaction with 2,5-dimethoxytetrahydro furan. The acetoxyacetyl derivatives of 14 and 15 were prepared and su bmitted to BBr3-promoted rearrangement. Acetylation of the resulting ( 2-acetoxyacetyl)pyrrol-1-yl-2-ethanol and 2-propanol furnished the cor responding acetates.