ASYMMETRIC-SYNTHESIS OF CYCLOPENTYLAMINE DERIVATIVES, INTERMEDIATES FOR CARBOCYCLIC NUCLEOSIDE SYNTHESIS - CARBOCYCLIZATION OF 2-AMINO-5-HEXENYL RADICALS

Authors
MARCOCONTELLES J BERNABE M
Citation
J. Marcocontelles et M. Bernabe, ASYMMETRIC-SYNTHESIS OF CYCLOPENTYLAMINE DERIVATIVES, INTERMEDIATES FOR CARBOCYCLIC NUCLEOSIDE SYNTHESIS - CARBOCYCLIZATION OF 2-AMINO-5-HEXENYL RADICALS, Tetrahedron letters, 35(34), 1994, pp. 6361-6364
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
34
Year of publication
1994
Pages
6361 - 6364
Database
ISI
SICI code
0040-4039(1994)35:34<6361:AOCDIF>2.0.ZU;2-B
Abstract
The carbocyclization of 2-amino-5-hexenyl radicals leading to aminocyc lopentane derivatives is described for the first time. The tributyltin hydride + AIBN mediated free radical cyclization of the chiral recurs ors 17-19 and 24 gives compounds 25, 27 and 28, respectively, in good yield.