Jc. Hedreen et al., A QUICK SILVER METHOD FOR SENILE PLAQUES AND NEUROFIBRILLARY TANGLES IN PARAFFIN SECTIONS, Brain research bulletin, 35(3), 1994, pp. 279-284
A new silver method for senile plaques and neurofibrillary tangles (NF
T) in paraffin sections is presented. This new technique is rapid in e
xecution (15 min) and reveals senile plaques of all morphological type
s as well as NFT. The silver staining is spatially congruent with immu
nocytochemical staining for the beta-amyloid peptide (A beta) in adjac
ent sections.