PHYLOGENETIC ANALYSIS OF THE RPOB GENE FROM THE PLASTID-LIKE DNA OF PLASMODIUM-FALCIPARUM

Authors
GARDNER MJ GOLDMAN N BARNETT P MOORE PW RANGACHARI K STRATH M WHYTE A WILLIAMSON DH WILSON RJM
Citation
Mj. Gardner et al., PHYLOGENETIC ANALYSIS OF THE RPOB GENE FROM THE PLASTID-LIKE DNA OF PLASMODIUM-FALCIPARUM, Molecular and biochemical parasitology, 66(2), 1994, pp. 221-231
Citations number
43
Categorie Soggetti
Parasitiology,Biology
Journal title
Molecular and biochemical parasitology → ACNP
ISSN journal
01666851
Volume
66
Issue
2
Year of publication
1994
Pages
221 - 231
Database
ISI
SICI code
0166-6851(1994)66:2<221:PAOTRG>2.0.ZU;2-4
Abstract
Marlaria and other Apicomplexan parasites harbour two extrachromosomal DNAs. One is mitochondrial and the other is a 35-kb circle with some plastid-like features but whose provenance and function is unknown. In addition to genes from rRNAs, tRNAs and ribosomal proteins, the 35-kb circular DNA of Plasmodium falciparum carries an rpoBC operon which e ncodes subunits of a eubacteria-like RNA polymerase. The phylogenetic analysis of the complete rpoB sequence presented here supports our inf erence that the 35-kb circle is the remnant of a plastid genome.