Clonal dissemination of two different MRSA strains, both clumping fact
or negative, has been observed in Germany for more than a year. Both s
trains possess the mec-A determinant and each exhibits a characteristi
c genomic DNA fragment pattern. One strain has spread in the north, th
e other in the south-west of Germany. Intensive care units are mainly
affected by MRSA-infections and probably play a special role in furthe
r intra- and inter-hospital spread.