We present a case of epidermoid carcinoma arising in Warthin's tumour
of parotid gland in an 80-year-old woman. Light microscopy revealed sm
all foci typical of benign Warthin's tumour with transition to epiderm
oid carcinoma. Immunohistochemical and ultrastructural observations co
nfirmed the epidermoid features of the malignant cells. The differenti
al diagnosis of a metastasis from an epidermoid carcinoma to the strom
a of Warthin's tumour and also of the so-called metaplastic variant of
Warthin's tumour is discussed.