EFFECT OF 4 IV INDUCTION-AGENTS ON T-LYMPHOCYTE PROLIFERATIONS TO PHAIN-VITRO

Authors
DEVLIN EG CLARKE RSJ MIRAKHUR RK MCNEILL TA
Citation
Eg. Devlin et al., EFFECT OF 4 IV INDUCTION-AGENTS ON T-LYMPHOCYTE PROLIFERATIONS TO PHAIN-VITRO, British Journal of Anaesthesia, 73(3), 1994, pp. 315-317
Citations number
11
Categorie Soggetti
Anesthesiology
Journal title
British Journal of Anaesthesia → ACNP
ISSN journal
00070912
Volume
73
Issue
3
Year of publication
1994
Pages
315 - 317
Database
ISI
SICI code
0007-0912(1994)73:3<315:EO4IIO>2.0.ZU;2-5
Abstract
Anaesthetic agents are believed to have an adverse effect on human imm unity. We have studied the effects of four i.v. induction agents, thio pentone, methohexitone, etomidate and propofol, on T-lymphocyte prolif erations to phytohaemagglutinin in vitro. We found that at plasma conc entrations similar to those obtained after induction doses, all drugs, with the exception of propofol, caused depression of T-lymphocyte fun ction.