M. Chen et al., IN-VIVO P-31 NMR-STUDIES OF ORIENTATION EFFECTS UPON RAT-BRAIN METABOLISM DURING MILD HYPOXIA, Magnetic resonance in medicine, 32(3), 1994, pp. 401-404
Energy metabolites in rat brain under the same level of hypoxia were m
onitored by P-31 NMR in both horizontal and vertical magnets. The chan
ges in PCr, P-i, and pHi in the vertical setting toward the end of hyp
oxia were significantly larger and the recovery in the horizontally he
ld animals was more complete. The results demonstrated quantitatively
that the stress of the alignment is superimposed on the stress of hypo
xia in the vertical magnet.