We present a general method to obtain a closed finite formula for the
exponential map from the Lie algebra to the Lie group for the defining
representation of orthogonal groups. Our method is based on the Hamil
ton-Cayley theorem and some special properties of the generators of th
e orthogonal group and is also independent of the metric. We present a
n explicit formula for the exponential of generators of the SO+(p, q)
groups with p + q = 6, in particular, dealing with the conformal group
SO+(2, 4) which is homomorphic to the SU(2, 2) group. This result is
needed in the generalization of U(1)-gauge transformations to spin-gau
ge transformations where the exponential plays an essential role. We a
lso present some new expressions for the coefficients of the secular e
quation of a matrix.