F. Bonte et al., DETERMINATION OF RETINOIC ACID LIPOSOMAL ASSOCIATION LEVEL IN A TOPICAL FORMULATION, Drug development and industrial pharmacy, 20(16), 1994, pp. 2527-2534
A new liposomal formulation containing a lower dose of drug and posses
sing increased skin bioavailability has recently been proposed. This p
aper describes a method to quantitatively determine the levels of reti
noic acid associated with liposomes in a marketable topical gel.