BIOASSAY QUANTITATION OF RAMOPLANIN IN HUMAN AND IN NONPRIMATE SERA

Authors
KENNY MT BRACKMAN MA DULWORTH JK
Citation
Mt. Kenny et al., BIOASSAY QUANTITATION OF RAMOPLANIN IN HUMAN AND IN NONPRIMATE SERA, Diagnostic microbiology and infectious disease, 18(2), 1994, pp. 117-119
Citations number
7
Categorie Soggetti
Microbiology,"Infectious Diseases
Journal title
Diagnostic microbiology and infectious disease → ACNP
ISSN journal
07328893
Volume
18
Issue
2
Year of publication
1994
Pages
117 - 119
Database
ISI
SICI code
0732-8893(1994)18:2<117:BQORIH>2.0.ZU;2-7
Abstract
This study developed and validated a bioassay for ramoplanin in human, dog, rabbit, and rat sera. Mean analyte recoveries and coefficients o f variation for duplicate assays with each serum using coded and spike d (30-720 ng/ml) samples ranged from 93.5% to 106.3% and from 1.8% to 5.4% respectively. All correlation coefficients were > 0.99 and, for e ach serum, there was no significant difference in overall analyte reco very between the 2 test days.