W. Kudelska et al., SYNTHESIS OF UNPROTECTED 2-DEOXYGLYCOSYL DONORS, BINO-HEXOPYRANOSYL)-0,0-DIALKYLPHOSPHORODITHIOATES, Polish Journal of Chemistry, 68(9), 1994, pp. 1767-1773
Sugar-O-unprotected S-(2-deoxyglycosyl)phosphorodithioates were synthe
sized by two routes: 1) Addition of O,O-dialkylphosphorodithioic acids
to unsubstituted D-glucal 2) Deprotection of the adducts obtained by
addition of phosphorodithioic acids to 4,6-O-isopropylidene-D-glucal.
These sugar-O-unprotected 2-deoxyglycosyl phosphorodithioates were obt
ained in high yield and their ability to act as glycosyl donors was de
monstrated.