TOTAL SYNTHESIS OF CORIANDRIN

Citation
Ga. Kraus et J. Ridgeway, TOTAL SYNTHESIS OF CORIANDRIN, Journal of organic chemistry, 59(17), 1994, pp. 4735-4737
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
00223263
Volume
59
Issue
17
Year of publication
1994
Pages
4735 - 4737
Database
ISI
SICI code
0022-3263(1994)59:17<4735:TSOC>2.0.ZU;2-I
Abstract
Coriandrin, an antiviral agent, has been synthesized in nine steps fro m diketone 3. The key steps in the synthesis include an efficient arom atization reaction using N-bromosuccinimide and a palladium-mediated c oupling of a benzylic bromide with a vinyl stannane.