N. Beyers et al., DELAY IN THE DIAGNOSIS, NOTIFICATION AND INITIATION OF TREATMENT AND COMPLIANCE IN CHILDREN WITH TUBERCULOSIS, Tubercle and lung disease, 75(4), 1994, pp. 260-265
Setting: The mortality and morbidity from childhood tuberculosis may b
e influenced by the delay from the time of first symptoms until the st
art of and compliance with treatment. Objective: This study investigat
ed these delay periods and the compliance with therapy in children wit
h tuberculosis. Design: During the study period there were 49 children
with probable and 123 with confirmed pulmonary tuberculosis (WHO crit
eria). The mean period from first symptoms until presentation was 4.3
weeks, from presentation until notification 5 weeks and from notificat
ion until therapy 0.9 weeks. 16% of children notified as having tuberc
ulosis never received therapy. Significantly fewer children in the urb
an squatter communities received therapy than in urban settled (P = 0.
02), rural agricultural (P = 0.0001) and rural settled (P = 0.09) comm
unities. 12% of children did not complete their therapy. Conclusion: T
he delay in presentation ('patient delay') was shorter than the delay
in diagnosis ('doctor delay'). Failure to trace children and to comple
te therapy was particularly likely to occur in urban squatter communit
ies. Easier access to health care facilities may shorten the 'patient
delay' while greater awareness of tuberculosis and proper investigatio
n of children may shorten the 'doctor delay'.