The aim of this study was to obtain the cut point to determine an indi
vidual's seronegativity with respect to measles using commercial reage
nts. To determine the test sensitivity, the serum of 22 individuals 21
years of age or older, and a positive history of measles (positive co
ntrol group), was studied. For specificity, the serum of 22 children 1
5 to 24 months old, and no measles vaccination record nor positive his
tory of measles (negative control group), was analyzed. The antibodies
titer determination for both groups was done using the ELISA techniqu
e and the Brunell method, subsequently, as well as a ROC curve (Receiv
ed Operating Curve). When the Brunell method was used, the cut points
were 0.4090 (sensitivity 1.0 and specificity 0.95) and 0.5042 (sensiti
vity 0.95 and specificity 1.0). When a ROC curve was done the cut poin
t was 0.4500, with a sensitivity and specificity of 100 per cent. It w
as also concluded that the latter is the best method to obtain this cu
t point, because it does not establish arbitrary values when the data
distribution does not follow a normal pattern.