About 30% of patients who have a Roux-en-Y gastrojejunostomy after gas
trectomy suffer from abdominal pain, nausea, vomiting of food and bloa
ting made worse by eating. This syndrome, called the Roux stasis syndr
ome, is caused, in part, by a motility disorder of the Roux limb. Tran
section of the jejunum during the construction of the limb separates t
he limb from the natural small intestinal pacemaker located in the duo
denum. Ectopic pacemakers then appear in the limb and trigger retrogra
de contractions in its proximal portion. These contractions slow trans
it through the limb and result in Roux stasis. Current nonsurgical tre
atment of the syndrome includes the use of prokinetic agents and intes
tinal pacing, neither of which has demonstrated long-term benefits. A
near-total gastrectomy may speed upper gastrointestinal transit somewh
at, but stasis in the Roux limb often persists. Our current approach a
ims at preventing the syndrome by the use of an 'uncut' Roux limb, an
operation which preserves myoneural continuity between the duodenal pa
cemaker and the Roux limb and so prevents the appearance of ectopic pa
cemakers and stasis in the limb.