INCREASE CAUSED BY INTERLEUKIN-6 IN PROMOTER ACTIVITY OF GUINEA-PIG LIVER TRANSGLUTAMINASE GENE

Authors
IKURA K SHINAGAWA R SUTO N SASAKI R
Citation
K. Ikura et al., INCREASE CAUSED BY INTERLEUKIN-6 IN PROMOTER ACTIVITY OF GUINEA-PIG LIVER TRANSGLUTAMINASE GENE, Bioscience, biotechnology, and biochemistry, 58(8), 1994, pp. 1540-1541
Citations number
14
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
58
Issue
8
Year of publication
1994
Pages
1540 - 1541
Database
ISI
SICI code
0916-8451(1994)58:8<1540:ICBIIP>2.0.ZU;2-M
Abstract
A 5'-flanking region (-2024 to +61) of the guinea pig liver transgluta minase gene and some 5'-deletion mutants were tested for promoter acti vity in human hepatoblastoma HepG2 cells treated with interleukin-6 (I L-6) by an assay of the transient expression of the chloramphenicol ac etyltransferase reporter gene. The promoter activity of the 5'-flankin g region introduced into the HepG2 cells was increased by IL-6.