A series of new derivatives of cholesterol bearing polar functional gr
oups on carbon-19 were synthesized, including 19-oximino-, 19-amino-,
19-(methylimino)-, 19-(methylamino)-, 19-mercapto-, and 19-(methylthio
)cholesterol, and 3beta-hydroxycholest-5-en-19-oic acid, as well as an
unusual cyclosterol, 5,19-cyclocholest-6-en-3beta-ol.