ADAPTIVE RESPONSE TO IONIZING-RADIATION I N NORMAL HUMAN SKIN FIBROBLASTS - ENHANCEMENT OF DNA-REPAIR RATE AND MODULATION OF GENE-EXPRESSION

Authors
AZZAM E DETOLEDO SM RAAPHORST GP MITCHEL REJ
Citation
E. Azzam et al., ADAPTIVE RESPONSE TO IONIZING-RADIATION I N NORMAL HUMAN SKIN FIBROBLASTS - ENHANCEMENT OF DNA-REPAIR RATE AND MODULATION OF GENE-EXPRESSION, Journal de chimie physique et de physico-chimie biologique, 91(7-8), 1994, pp. 931-936
Citations number
11
Categorie Soggetti
Biology,"Chemistry Physical
Journal title
Journal de chimie physique et de physico-chimie biologique → ACNP
Volume
91
Issue
7-8
Year of publication
1994
Pages
931 - 936
Database
ISI
SICI code
Abstract
Low doses and dose rates of ionizing radiation enhance the rate of DNA repair in human fibroblasts and protect the cells against radiation-i nduced micronucleus formation. Chronic exposures reduce the mRNA level s of the genes topoisomerase II and FACC-1 (Fanconi's anemia, group C) .