L. Decatte et al., FETAL HYPOTHYROIDISM AS A COMPLICATION OF AMIODARONE TREATMENT FOR PERSISTENT FETAL SUPRAVENTRICULAR TACHYCARDIA, Prenatal diagnosis, 14(8), 1994, pp. 762-765
We present a case of persistent fetal supraventricular tachycardia whe
re transplacental and direct fetal treatment with amiodarone caused an
iatrogenic hypothyroidism. This condition was successfully managed wi
th the intra-amniotic instillation of 250 mu g of L-thyroxine weekly,
for 3 weeks. A male infant was delivered at 32 weeks by Caesarean sect
ion. The neonatal electrocardiogram showed Wolf-Parkinson-White (WPW)
syndrome, which was controlled by digoxin alone. Thyroid function norm
alized quickly and the baby is developing normally.