Sj. Tu et al., SIMULATION OF BIDIRECTIONAL ULTRASOUND HYPERTHERMIA TREATMENTS OF NECK TUMORS, International journal of hyperthermia, 10(5), 1994, pp. 707-722
The temperature distributions produced in neck tumours by using either
a single, scanned transducer (a unidirectional scan) or two separate
transducers whose axis are perpendicular (a bidirectional scan) were s
imulated. The three-dimensional neck model included separate anatomica
l regions for the normal neck muscle tissue, the tumour, the spinal co
lumn and the trachea (no large blood vessels). The effets of variation
s in the transducer frequency and f number, the tumour size and locati
on, and the normal and tumour blood perfusion rates were studies. The
best simulated temperature distributions were produced by bidirectiona
lly scanned, 2 MHz, f number 2.0 ultrasound transducers whose powers w
ere modulated as a function of position. The simulated temperature dis
tributions from such modulated bidirectional scans were significantly
better than those of both unidirectional and unmodulated bidirectional
scans. The 1-MHz transducers generally produced hot spots at the tiss
ue-spine and/or tissue-trachea interface. The 3-MHz transducers elimin
ated those deep hot spots but created other hot spots close to the ski
n surface, and did not adequately heat the deeper regions of the tumou
r. These results from the simplified computer simulations may be used
to guide the construction of improved ultrasound hyperthermia systems
for the treatment of neck tumours.