We have found that a remarkable improvement in the resolution of the d
etails and in the richness of halftones can be obtained using 4'' x 5'
' black-and-white professional firms specifically prepared for scienti
fic and documentary photography. Through modification of the developin
g time and developer dilution, a close control of the contrast and gra
y tones is also possible. Using this large-format film, a contact prin
t can be made and top-quality pictures obtained even for a subject as
difficult as skin pathology.