MICROBIAL-PRODUCTION OF OPTICALLY-ACTIVE 1,2-DIOLS USING RESTING CELLS OF ALCALIGENES SP DS-S-7G

Authors
SUZUKI T KASAI N MINAMIURA N
Citation
T. Suzuki et al., MICROBIAL-PRODUCTION OF OPTICALLY-ACTIVE 1,2-DIOLS USING RESTING CELLS OF ALCALIGENES SP DS-S-7G, Journal of fermentation and bioengineering, 78(2), 1994, pp. 194-196
Citations number
11
Categorie Soggetti
Food Science & Tenology","Biothechnology & Applied Migrobiology
Journal title
Journal of fermentation and bioengineering → ACNP
ISSN journal
0922338X
Volume
78
Issue
2
Year of publication
1994
Pages
194 - 196
Database
ISI
SICI code
0922-338X(1994)78:2<194:MOO1UR>2.0.ZU;2-O
Abstract
A novel generation method of optically active 1,2-diols with excellent optical purity (>98% enantiomeric excess) from their racemates was de veloped using the resting cells of Alcaligenes sp. DS-S-7G. This metho d was based on microbial enantioselective oxidation of the racemic 1,2 -diols. When 1% (v/v) 1,2-butanediol was used as a substrate, the degr adation reaction in the presence of NAD(+) could be carried out 8 time s within 200 h.