LOSS OF Y-CHROMOSOME - AN AGE-RELATED EVENT OR A CYTOGENETIC MARKER OF A MALIGNANT CLONE

Authors
ABELIOVICH D YEHUDA O BENNERIAH S OR R
Citation
D. Abeliovich et al., LOSS OF Y-CHROMOSOME - AN AGE-RELATED EVENT OR A CYTOGENETIC MARKER OF A MALIGNANT CLONE, Cancer genetics and cytogenetics, 76(1), 1994, pp. 70-71
Citations number
3
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
76
Issue
1
Year of publication
1994
Pages
70 - 71
Database
ISI
SICI code
0165-4608(1994)76:1<70:LOY-AA>2.0.ZU;2-X
Abstract
Cytogenetic analysis of bone marrow cells performed at the time of dia gnosis of ALL in an 80-year-old male patient revealed two unrelated ab normal clones. One included the 9;22 translocation (Philadelphia chrom osome) as the sole aberration and the second was missing the Y chromos ome. The significance of this finding in the light of the role of - Y clone in malignancy is discussed.