Radiation injury to subclavian and axillary arteries is a rare and lat
e complication of radiotherapy. Until recently it has been treated alm
ost exclusively by carotid-brachial bypass surgery. We report three ca
ses who presented with severe upper limb ischaemia following previous
axillary radiotherapy for breast carcinoma. One patient with an axilla
ry artery occlusion failed angioplasty and required bypass surgery. A
further patient with an axillary artery occlusion was successfully man
aged by the percutaneous placement of an arterial stent. The third pat
ient with an isolated axillary artery stenosis responded to balloon an
gioplasty. All three patients remained asymptomatic. Percutaneous angi
oplasty and stent placement, where necessary, are appropriate first ch
oice treatment for delayed radiation stenosis and occlusion in upper l
imb ischaemia.