We report a meta-analysis of randomised, controlled, clinical trials o
f systemic anti-fibrinolytics in traumatic hyphaema. Outcome measures
were rate of secondary haemorrhage and final visual acuity. An estimat
e of the overall odds ratio for each outcome measure was calculated bo
th by combining the logarithms of the odds ratios, and by the Mantel-H
aenszel method. The results confirm a beneficial effect of systemic an
tifibrinolytics on the rate of secondary haemorrhage, but not on final
visual acuity.