A COMPARISON OF AMETHOCAINE CREAM WITH LIGNOCAINE-PRILOCAINE CREAM (EMLA) FOR REDUCING PAIN DURING RETROBULBAR INJECTION

A prospective, randomised, double-masked, placebo-controlled study was carried out on 169 patients undergoing cataract extraction to compare the topical anaesthetic cream amethocaine with EMLA (eutetic mixture of local anaesthetic, lignocaine and prilocaine) and placebo in reduci ng pain during retrobulbar injection. Fifty-eight patients received EM LA, 55 amethocaine and 56 the placebo. The pain was assessed objective ly by the anaesthetist and subjectively by the patient. Significantly lower pain scores were observed in those patients who had amethocaine (p<0.001) or EMLA p<0.005) in comparison with those who had placebo, b ut there was no statistical difference between amethocaine and EMLA (p >0.1; t-test). No systemic or local side-effects were encountered in a ny group.